Stress affects the microbiome in a number of ways also. It can lead to leaky gut, an immune response, and high inflammation levels. Stress can cause an imbalance of the bacteria in the microbiome. Small intestine bacterial overgrowth may occur, leading to serious problems with digestion. A slowing of gut motility also leads to serious problems with digestion and absorption of nutrients.
Common Symptoms of Neuroaffect Circuit Dysfunction
- Anxiety is one of the most frequently seen. For people with AFS, the anxiety is typically a result of disordered thinking that leads the person to believe they will never be better. Discouragement and the negative thinking that can come from it can lead to the development of health anxiety, a more serious condition. With health anxiety, the person misinterprets and exaggerates physical signs and symptoms, thinking they are indicators of a more serious condition developing. The effects of norepinephrine and epinephrine can contribute to this anxiety.
- Depression, a frustration with the medical system, feelings of sadness and defeat, also can result from a dysfunctional Neuroaffect circuit. An imbalance of serotonin and dopamine is often at the bottom of this feeling. The amount of cortisol and the timing of its release are also implicated in developing this kind of depression.
- Feelings of impending doom may be due to physical symptoms below the level of awareness. They may be the precursors of significant symptoms later. However, stress may also be a culprit.
- Neurodegeneration, the loss of neurons, is one of the main causes of age-related chronic illness conditions. Stress is a major factor in the loss of neurons. Pro-inflammatory cytokines produced by stress play a major role in this loss also.
- Lowered stress tolerance may be due to low serotonin levels and the release of CRF. In this condition, even the smallest stressor may trigger large responses.
- Sleeplessness, either onset or maintenance, is a major problem with a dysfunctional Neuroaffect circuit. High cortisol levels at the wrong time and low blood sugar levels have been implicated in both of these conditions.
Conditions Related to Neuroaffect Circuit Dysfunction
- Mood Disorders
- Sleep Maintenance Insomnia
- Sleep Onset Insomnia
- Neurotransmitter Imbalance
- Autism Spectrum Disorder
- Alzheimer’s Dementia
- Parkinson’s Disease
- Intractable Eye Twitching
- Multiple Sclerosis
- Panic Disorder