What is Peptide Therapy?
Your body uses peptides as signaling molecules for biological pathways and as hormones. They bind to receptors on the surface of cells, where they communicate with other cells and instruct them on what to do. Their action is fast, short-acting, and because they are “upstream” signaling agents, they tend to be more broadly focus on influencing multiple chemical pathways. For example, insulin, which is the most famous peptide, binds to a cell’s receptor and tells the cell to bring glucose into the cell. Peptides supply a remediation approach resembling natural pathways. This allows changes inside your body that closely mimic your body’s natural structures. Since peptides regulate various functions of your body (such as the ability to lose weight, function sexually, or digest foods adequately), peptide therapy holds promise for many significant interventions, especially in regenerative and anti-aging medicine.
This peptide has proven to be very stable, resistant to breakdown in both water and enzymes found in gastric juices. For this reason, BPC-157 is one of the few peptides that can be ingested by mouth for some purposes, unlike many other peptides that get broken down by gastric juices and thus have to be administered subcutaneously. It also can be given by injection just under the skin, injection into muscles, and through the nasal passages. BPC-157 appears to work on several systems of the body. Its effects take place through its signaling properties. It works to control inflammation throughout the body. It also strengthens the production of proteins used in the healing process. Through its signaling properties, this peptide significantly affects the healing process. In its role in tissue and bone repair, this peptide influences the expression of growth hormone. This allows for more cell growth. It also works to increase the production of collagen. Also, it directly affects the stimulation of tyrosine kinase which increases the production of proteins.
CJC-1295 / Ipamorelin
CJC-1295 and Ipamorelin is a combination of two peptides that work together to achieve the same purpose. With different approaches, the combination increases the effectiveness of the two peptides. CJC-1295 consists of a chain of 30 amino acids that function to stimulate the pituitary gland to release growth hormone. Ipamorelin also works as a peptide to specifically target receptors for ghrelin. Ghrelin is the hormone that increases when you feel hungry to encourage you to eat, then decreases when you’re full. The combination of these two peptides works to increase the production and release of growth hormone naturally. Increasing growth hormone works to help cells multiply and allow growth to take place. CJC1295 works as a growth hormone-releasing hormone, signaling receptors on the pituitary to increase growth hormone. Ipamorelin also works to stimulate the pituitary gland to produce and release growth hormone by stimulating free calcium in the pituitary. Working together, these peptides increase the amount of growth hormone released by the pituitary.
Thymosin Alpha 1
Its influence on your immune system depends on how much your immune system is unbalanced and how great the level of inflammation is in your body. It is able to perform multiple tasks as a peptide in your body. Thymosin Alpha 1 operates by either increasing the function of your immune system when it needs to work more or by down-regulating its function when it needs to work less. This ability is called pleiotropism, or the ability to have multiple effects from one peptide. One of the major functions of Thymosin Alpha 1 involves balancing the Th1 and TH2 branches of your immune system.
Thymosin Beta 4 (TB4)
TB4 performs multiple functions in its role as a healing peptide. Some of the major roles for TB4 include speeding up the process of growing new cells, aiding in the movement of cells from their place of origin to the sites of injuries, and helping cells change from one kind to another. All of these processes increase the effectiveness of injury healing. Regarding the healing of wounds, TB4 helps in growing new blood vessels, lowering inflammation, and lessening scar tissue formation. It also greatly increases the activity of actin, which is a major part of cell structure and movement. In addition, TB4 works to reduce inflammation, inhibit the growth of microbes at the site of wounds, and reduce cell death. Also, it reduces damage to cells from toxins in the body.
GHK-CU, LL-37, DSIP, MGF, GHRP-2, Semax, Selank, AOD-9604, ARA 290, IRGD, MOTS-c, Melanotan, PT141.
Although peptide therapy has a very rare side effect profile, some can appear. The reason there are so few side effects is that the amino acids can disassociate after doing its job, rather than having to be metabolized by the liver or the kidneys. Potentially serious side effects may result from inappropriate usage of peptides without a provider to guide you.
The following are the more likely side effects experienced with peptides:
- Injection site discomfort
- Changes in blood pressure, either increases or decreases depending on the peptide
- Fatigue and dizziness
- Hot or cold feelings
- Kidney and liver toxicity
- Potential toxicity to fetuses
- Abnormal heart rhythms
- Increased feelings of hunger
- Joint pain
- Tingling or numbness
- Water retention (this is a sign of overdose)
- Weight gain or loss
- Peptides with anabolic effects should not be considered for those with history or at risk of cancer
Peptides can be given subcutaneously, orally, topically, nasal spray, IV, or IM depending on its formulation.